#53 – Florence, SC
3390 North Williston Road
Florence, SC
120 gas pumps
Find South Carolina's Buc-ee's store serving the I-95 corridor
This South Carolina Buc-ee's locations guide is part of our complete Buc-ee's Locations Directory. Explore all 1 Buc-ee's locations in South Carolina and discover what makes each one unique.
South Carolina's Buc-ee's in Florence has become one of the most important stops on the East Coast's busiest highway corridor. Positioned at the junction of I-95 and I-20, it serves the steady stream of travelers making their way between the Northeast and Florida, as well as those heading to Myrtle Beach and the South Carolina coast.
For millions of road trippers making the annual migration to Florida beaches or Disney World, the Florence Buc-ee's marks a significant milestone—you've made it to South Carolina, and quality food and clean restrooms are just ahead. It's become a landmark on one of America's most traveled routes.
The Florence location offers the full mega-store experience with all the amenities you'd expect from Buc-ee's. Check the details below for everything you need to plan your stop.
3390 North Williston Road
Florence, SC
120 gas pumps
Expected: 2031
South Carolina's second Buc-ee's is planned for Hardeeville at Exit 8 off I-95, part of the larger Hardee Station mixed-use development, expected to open in 2031.
Florence Buc-ee's marks the South Carolina milestone on this epic drive, perfectly positioned for a break before or after the state line.
Florence is accessible from I-95 for those taking the I-95 to US-501 route to the beach.
Quick interstate drive for those connecting between South Carolina's capital and the I-95 corridor.
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South Carolina's lone Buc-ee's in Florence punches well above its weight in terms of traffic volume. Its position at the I-95/I-20 junction makes it a natural stop for travelers heading in multiple directions—south to Florida, east to Myrtle Beach, or west to Columbia and beyond.
The store serves as a quality alternative to the outdated tourist traps and mediocre rest stops that have long characterized this stretch of I-95. For travelers who remember endless miles with few good options, the Florence Buc-ee's represents a welcome upgrade.
Like all Buc-ee's locations, Florence operates 24/7 with fresh food, spotless restrooms, and the full range of snacks and merchandise. Whether you're just topping off the tank or settling in for a proper break, this store delivers the consistent Buc-ee's experience.
Check out our road trip guide for the best routes and travel tips.
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